منابع مشابه
Engineering channels: atomic biology.
I on channels are protein valves that control an enormous range of biological function. Atomic-scale properties of channel proteins control macroscopic flows across otherwise insulating membranes of cells and subcellular compartments, and so the study of channels is a study in atomic biology. Ion channels are intrinsically multiscale devices that allow the amino acid side chains of a protein to...
متن کاملAtomic Biology, Electrostatics, and Ionic Channels
The identification and manipulation of the molecules of life is one of the triumphs of man, putting biological systems under his control, embedding them into his technology, allowing the control of many of life's functions. In the next few years some of the dreams of centuries will become realities, as we learn to control disease and our biological life cycle in ways that only poets and novelis...
متن کاملDevelopment of Nano-Biology with Atomic Force Microscopy
The first observation of double-stranded DNA by atomic force microscopy in the late 1980’s greatly encouraged many biological researchers to jump into the nanoworld. Here we briefly review the history of how AFM has been utilized to reveal nanometer-scale structures of DNA-protein complexes, and we highlight key technical developments that have accelerated applications of AFM to molecular biolo...
متن کامل`Atomic resolution': a badly abused term in structural biology.
The term ‘atomic resolution’ was defined a long time ago and it is generally accepted to correspond to an electron-density map (or a map calculated using another type of data, for example nuclear density) in which individual atoms can be distinguished. It is usually assumed to correspond to a resolution dmin of 1.2 Å of the diffraction data, which is also known as the ‘Sheldrick criterion’ (She...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Heredity
سال: 2005
ISSN: 0018-067X,1365-2540
DOI: 10.1038/sj.hdy.6800628